C7499
CK-548
≥98% (HPLC)
别名:
2-(3-Bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-4-thiazolidinone, CK-0993548
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关于此项目
经验公式（希尔记法）:
C15H11BrClNO2S
化学文摘社编号:
分子量:
384.68
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
InChI
1S/C15H11BrClNO2S/c16-10-3-1-2-9(6-10)15-18(14(20)8-21-15)12-7-11(17)4-5-13(12)19/h1-7,15,19H,8H2
SMILES string
Oc1ccc(Cl)cc1N2C(SCC2=O)c3cccc(Br)c3
InChI key
KEGQNJITMFBVAC-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
solubility
DMSO: 24 mg/mL
storage temp.
2-8°C
Biochem/physiol Actions
CK-548 inhibits the activity of actin-related protein (Arp)2/3 complex by inserting into the hydrophobic core of Arp3 and altering its conformation.
CK-548 inhibits the activity of actin-related protein (Arp)2/3 complex by inserting into the hydrophobic core of Arp3 and altering its conformation: inhibits
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Molecular biology of the cell, 31(18), 2002-2020 (2020-06-25)
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Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is one of the leading global causes of virus-induced encephalitis. The infectious life-cycle of viruses is heavily dependent on the host membrane trafficking network. Here, we have performed a RNA-interference-based screen using a
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