C8289
Clebopride maleate salt
~95%
别名:
4-(4-Amino-5-chloro-2-methoxybenzamido)-1-benzylpiperidine
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经验公式（希尔记法）:
C20H24ClN3O2 · C4H4O4
化学文摘社编号:
分子量:
489.95
UNSPSC Code:
51101500
PubChem Substance ID:
MDL number:
InChI
1S/C20H24ClN3O2.C4H4O4/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14;5-3(6)1-2-4(7)8/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25);1-2H,(H,5,6)(H,7,8)/b;2-1+
SMILES string
OC(=O)\C=C\C(O)=O.COc1cc(N)c(Cl)cc1C(=O)NC2CCN(CC2)Cc3ccccc3
InChI key
BCVIWCRZYPHHMQ-WLHGVMLRSA-N
assay
~95%
storage temp.
2-8°C
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Ki-Suk Kim et al.
International journal of toxicology, 26(1), 25-31 (2007-03-17)
The inhibition of the potassium current I(Kr) and QT prolongation has been known to be associated with drug-induced torsades de pointes arrhythmias (TdP) and sudden cardiac death. In this study, the authors investigated the cardiac electrophysiological effects of clebopride, a
I S Stovolosov et al.
Bulletin of experimental biology and medicine, 150(3), 281-285 (2011-01-18)
Administration of D(2) receptor antagonist clebopride in a dose not affecting locomotor activity was followed by a decrease in maternal bonding behavior of 10-day-old and 15-day-old albino rat pups. D(1) receptor antagonist SCH23390 had a stimulatory effect only on the
R Cuena Boy et al.
Atencion primaria, 21(5), 289-295 (1998-06-03)
To clarify if there is any basis for the hypothesis that Clebopride leads to more extrapyramidal reactions than Metoclopramide. Observational, longitudinal, retrospective and comparative study of two series of cases. The entire Spanish healthcare system. Those notified to the Spanish
Hemi-restless legs syndrome induced by clebopride.
R Erro et al.
European journal of neurology, 19(6), e59-e59 (2012-05-15)
Zhirong Tan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(23), 2072-2076 (2010-07-06)
A sensitive and specific liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS/MS) method has been developed and validated for the identification and quantification of clebopride in human plasma using itopride as an internal standard. The method involves a simple liquid-liquid extraction. The analytes
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