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关于此项目
经验公式(希尔记法):
C27H27N2O4F
化学文摘社编号:
分子量:
462.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
assay
≥98% (TLC)
form
solid
solubility
DMSO: 20 mM, clear to slightly hazy, colorless to faintly yellow
storage temp.
−20°C
SMILES string
FCC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc3ccccc3
InChI
1S/C27H27FN2O4/c28-18-25(31)23(16-20-10-4-1-5-11-20)29-26(32)24(17-21-12-6-2-7-13-21)30-27(33)34-19-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2,(H,29,32)(H,30,33)/t23-,24-/m0/s1
InChI key
CAILNONEKASNSH-ZEQRLZLVSA-N
Application
Cathepsin B and Cathepsin L inhibitor
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Chris W Lee et al.
Molecular neurodegeneration, 12(1), 55-55 (2017-07-27)
Haploinsufficiency of GRN, the gene encoding progranulin (PGRN), causes frontotemporal lobar degeneration (FTLD), the second most common cause of early-onset dementia. Receptor-mediated lysosomal targeting has been shown to regulate brain PGRN levels, and complete deficiency of PGRN is a direct
Shogo Kikuta et al.
Neuroscience letters, 636, 120-126 (2016-11-08)
Oxygen and glucose deprivation (OGD) elicits a rapid and irreversible depolarization with a latency of ∼5min in intracellular recordings of hippocampal CA1 neurons in rat slice preparations. In the present study, we examined the role of cathepsin L in the
Tomohiko Fujii et al.
Bioconjugate chemistry, 25(10), 1838-1846 (2014-09-10)
It is difficult to completely remove carcinomas in unguided ablative surgery because they cannot be distinguished with the unaided human eye. Therefore, in order to precisely visualize tiny tumors and the borders between cancerous lesions and normal tissues, we have
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