phospho-Epidermal Growth Factor Receptor (pTyr¹⁰⁶⁸) ELISA human

The assay is designed for the quantitative determination of epidermal growth factor receptor.

phospho-Epidermal Growth Factor Receptor (pTyr¹⁰⁶⁸) ELISA detects EGFR phosphorylated at tyrosine 1068 in cell lysates and biological fluids.

EGFR, a member of the family of receptor tyrosine kinases, is a full length, type I transmembrane glycoprotein. In vivo phosphorylation of EGFR specific tyrosine sites, including Tyr¹¹⁷³ or Tyr¹⁰⁶⁸, activates EGFR and downstream molecules.

EGFR ELISAs are fast (total time 4 hours), sensitive, and specific assays. The kit contains precoated plates, all incubations proceed at room temperature, and no proprietary equipment is required.

Specifically measures human EGFR protein phosphorylated on tyrosine 1068 with a sensitivity of <0.3 units/mL, which is 8 times more sensitive than immunoblotting. Does not detect non-phosphorylated EGFR.