D0160
16,16-二甲基前列腺素 E2
methyl acetate solution
别名:
16,16-二甲基-PGE2
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C22H36O5
化学文摘社编号:
分子量:
380.52
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
InChI
1S/C22H36O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-17,19-20,24-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,19-,20-/m1/s1
SMILES string
CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
InChI key
QAOBBBBDJSWHMU-WMBBNPMCSA-N
biological source
synthetic (organic)
assay
≥98% (HPLC)
form
methyl acetate solution
concentration
10 mg/mL
functional group
carboxylic acid
lipid type
unsaturated FAs
shipped in
wet ice
storage temp.
−20°C
Preparation Note
恢复由于冷冻而沉淀的溶液可能需要激越或短暂的超声处理。可以使用N2或真空除去乙酸甲酯。可以制备1-5 mg/mL的无水酒精储备溶液，并用等渗盐水稀释。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
target_organs
Central nervous system
supp_hazards
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
8.6 °F
flash_point_c
-13 °C
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
Tomonori Kunikata et al.
Digestive diseases and sciences, 47(4), 894-904 (2002-05-07)
We evaluated the effect of various PGE analogs specific to EP receptor subtypes on indomethacin-induced small intestinal lesions in rats and investigated the relationship of EP receptor subtype with the PGE action using EP receptor knockout mice. Animals were administered
Elena Piazuelo et al.
Prostaglandins & other lipid mediators, 81(3-4), 150-161 (2006-11-07)
Accumulating evidence suggests that COX-2-derived prostaglandin E(2) (PGE(2)) plays an important role in esophageal adenocarcinogenesis. Recently, PGE(2) receptors (EP) have been shown to be involved in colon cancer development. Since it is not known which receptors regulate PGE(2) signals in
Genhai Zhu et al.
Gynecologic oncology, 94(2), 422-426 (2004-08-07)
Emerging evidence supports a role for prostaglandins (PG) and their synthesizing enzyme, cyclooxygenase (COX), in tumor angiogenesis. The objective of this study was to investigate the effects of prostaglandin E(2) (PGE(2)) on the expression of vascular endothelial growth factor (VEGF)
Sara S Roscioni et al.
British journal of pharmacology, 162(1), 193-209 (2010-09-02)
Changes in airway smooth muscle (ASM) phenotype may contribute to the pathogenesis of airway disease. Platelet-derived growth factor (PDGF) switches ASM from a contractile to a proliferative, hypo-contractile phenotype, a process requiring activation of extracellular signal-regulated kinase (ERK) and p70(S6)
Corey Cutler et al.
Blood, 122(17), 3074-3081 (2013-09-03)
Umbilical cord blood (UCB) is a valuable source of hematopoietic stem cells (HSCs) for use in allogeneic transplantation. Key advantages of UCB are rapid availability and less stringent requirements for HLA matching. However, UCB contains an inherently limited HSC count
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持