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Merck
CN

D0188

Sigma-Aldrich

Anti-Deoxyribonuclease I (DNase I) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

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MDL编号:
UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen 33 kDa

种属反应性

bovine

浓度

1.0 mg/mL

技术

microarray: suitable
western blot: 1 μg/mL using bovine pancreatic DNase I

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

bovine ... DNASE1(282217)

一般描述

The enzyme is Ca2+ and Mg2+ dependent. It is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum.

免疫原

bovine pancreatic deoxyribonuclease I (DNase I).

应用

Anti-Deoxyribonuclease I (DNase I) antibody produced in rabbit is suitable for microarray and western blotting at a working concentration of 1 μg/mL using bovine pancreatic DNase I.

生化/生理作用

DNase I is an endonuclease that hydrolyzes double-stranded or single-stranded DNA preferentially at sites adjacent to pyrimidine nucleotides to produce a complex mixture of 5′-phosphate mononucleotides and oligonucleotides.

外形

Solution in phosphate buffered saline, pH 7.2, containing 0.01% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S Shak et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(23), 9188-9192 (1990-12-01)
Respiratory distress and progressive lung destruction in cystic fibrosis can be attributed to bacterial persistence and the accumulation of viscous purulent secretions in the airways. More than 30 yr ago it was suggested that the large amounts of DNA in

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