D029
R(−)-2,10,11-Trihydroxyaporphine hydrobromide
>97%, small crystals
别名:
R(−)-2-Hydroxyapomorphine hydrobromide
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关于此项目
经验公式（希尔记法）:
C17H17NO3 · HBr
化学文摘社编号:
分子量:
364.23
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
>97%
form
small crystals
optical activity
[α]21/546 −103.6°, c = 0.4 in methanol(lit.)
color
gray to green
solubility
H2O: moderately soluble (dissolve in oxygen-free boiled water containing 0.1% sodium metabisulfite or other antioxidants.), dilute aqueous acid: moderately soluble, ethanol: moderately soluble, methanol: soluble
storage temp.
2-8°C
SMILES string
Br[H].[H][C@]12Cc3ccc(O)c(O)c3-c4cc(O)cc(CCN1C)c24
Gene Information
human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
Biochem/physiol Actions
Dopamine receptor agonist.
Disclaimer
Photosensitive and hygroscopic
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
J L Neumeyer et al.
Journal of medicinal chemistry, 25(8), 990-992 (1982-08-01)
The enantiomers (6aR and 6aS) of 2,10,11-trihydroxyaporphine (THA) were synthesized from thebaine and bulbocapnine and evaluated pharmacologically in vitro in comparison with (-)-apomorphine [(-)-APO] and dopamine by competition with tritiated apomorphine, ADTN, and spiroperidol for binding to a membrane fraction
A E Lamers et al.
The American journal of physiology, 273(1 Pt 2), R387-R392 (1997-07-01)
A 7-day exposure of tilapia (Oreochromis mossambicus) to water with a pH of 4.5 activates their pituitary melanophore-stimulating hormone (MSH) cells to preferentially release diacetyl alpha-MSH as an important corticotrope (13). We here focus on the control of alpha-MSH release
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