D0875
Dansylglycine
fluorescent amino acid
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关于此项目
经验公式（希尔记法）:
C14H16N2O4S
化学文摘社编号:
分子量:
308.35
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
214-129-7
MDL number:
InChI
1S/C14H16N2O4S/c1-16(2)12-7-3-6-11-10(12)5-4-8-13(11)21(19,20)15-9-14(17)18/h3-8,15H,9H2,1-2H3,(H,17,18)
InChI key
QHFXORCWAQTTGH-UHFFFAOYSA-N
SMILES string
CN(C)c1cccc2c(cccc12)S(=O)(=O)NCC(O)=O
form
powder
technique(s)
ligand binding assay: suitable
storage temp.
−20°C
Application
Dansylglycine, an HSA drug site II probe, is used for the differentiation and analysis of specific binding sites on serum albumin. Dansylglycine is used to generate chromophore-modified cyclodextrins for use in chemosensor development.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
M Petersson et al.
Journal of chromatography. B, Biomedical sciences and applications, 714(1), 39-46 (1998-09-24)
This paper describes sample enrichment in a single levitated droplet for capillary electrophoresis (CE) analysis. The droplet was trapped in an acoustical field. The minute sample volumes needed for the enrichment procedure were precisely handled using a piezoelectric flow-through liquid
A Tamura et al.
Journal of pharmaceutical and biomedical analysis, 15(9-10), 1477-1482 (1997-06-01)
Separation process in a liquid chromatographic column were visualized and analyzed by a developed chromato-videoscope. The migration aspects were evaluated with successively obtained densitograms. In reversed-phase chromatography, the band widths of each solute band were almost equal fore both weakly
Laura H Lucas et al.
Journal of the American Chemical Society, 126(43), 14258-14266 (2004-10-28)
It is important to characterize drug-albumin binding during drug discovery and lead optimization as strong binding may reduce bioavailability and/or increase the drug's in vivo half-life. Despite knowing about the location of human serum albumin (HSA) drug binding sites and
J Bramhall
Biochemistry, 25(11), 3479-3486 (1986-06-03)
There are distinct differences in the molecular packing of phospholipid molecules in the inner and outer membrane monolayers of small lipid vesicles; a small radius of curvature imparts an asymmetry to the interface between these two monolayers. I have used
A E Thumser et al.
Journal of lipid research, 39(5), 1033-1038 (1998-06-04)
The binding of monoacylglycerides of long-chain fatty acids to human serum albumin has been examined using monooleoylglycerol as the ligand. Binding was investigated using changes in tryptophan fluorescence and also the displacement of a variety of well-studied fluorescent ligands from
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