生物来源
mouse
偶联物
unconjugated
抗体形式
ascites fluid
克隆
ZK-31, monoclonal
包含
15 mM sodium azide
种属反应性
human, animal
技术
indirect immunofluorescence: 1:400 using frozen sections of human tissue.
microarray: suitable
同位素/亚型
IgG1
运输
dry ice
储存温度
−20°C
基因信息
human ... DSC1(1823), DSC2(1824), DSC3(1825), DSG1(1828)
免疫原
human epidermal keratins
生化/生理作用
The antibody localizes an epitope on desmosomes, but does not show reaction with hemidesmosomes. The product may be used for immunoperoxidase and immunofluorescent staining of frozen sections of human and animal tissues or densely grown monolayers of human and animal cells.
法规信息
新产品
此项目有
J L R Williams et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 295(4), R1204-R1213 (2008-08-16)
Maintaining placental syncytiotrophoblast, a specialized multinucleated transport epithelium, is essential for normal human pregnancy. Syncytiotrophoblast continuously renews through differentiation and fusion of cytotrophoblast cells, under paracrine control by syncytiotrophoblast production of human chorionic gonadotropin (hCG). We hypothesized that K(+) channels
A B Lang et al.
Experimental cell biology, 54(2), 61-72 (1986-01-01)
Immunohistological analysis of human tissue using monoclonal antibodies against cytokeratins, which are confined to cells of epithelial origin, is a valuable technique. Using human epidermal keratins as antigen, we prepared monoclonal antibodies against cytokeratins (ZK1, ZK7, ZK61 and ZK99) and
Gavin P Collett et al.
PloS one, 5(5), e10529-e10529 (2010-05-14)
Fusion of placental villous cytotrophoblasts with the overlying syncytiotrophoblast is essential for the maintenance of successful pregnancy, and disturbances in this process have been implicated in pathological conditions such as pre-eclampsia and intra-uterine growth retardation. Caveolin-1 has been shown to
Gavin P Collett et al.
PloS one, 7(1), e30453-e30453 (2012-01-25)
Fusion of placental villous cytotrophoblasts with the overlying syncytiotrophoblast is essential for the maintenance of successful pregnancy, and disturbances in this process have been implicated in pathological conditions such as pre-eclampsia and intra-uterine growth retardation. In this study we examined
Pascale Gerbaud et al.
Endocrinology, 152(12), 5017-5028 (2011-09-29)
Placental development is markedly abnormal in trisomy 21 (T21) pregnancies. We hypothesized that abnormal paracrine cross talk between the fetal mesenchymal core and the trophoblast might be involved in the defect of syncytiotrophoblast formation and function. In a large series
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