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Merck
CN

D176

黄豆苷元

别名:

4′1,7-二羟基-异黄酮, 7-羟基-3-(4-羟基苯基)-4H-1-苯并吡喃-4-酮, 7-羟基-3-(4-羟基苯基)色酮, 异金司他丁

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经验公式(希尔记法):
C15H10O4
化学文摘社编号:
分子量:
254.24
EC Number:
207-635-4
UNSPSC Code:
12352204
MDL number:
Beilstein/REAXYS Number:
231523
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storage temp.

−20°C, 2-8°C

SMILES string

Oc1ccc(cc1)C2=COc3cc(O)ccc3C2=O

InChI

1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H

InChI key

ZQSIJRDFPHDXIC-UHFFFAOYSA-N

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Biochem/physiol Actions

大豆异黄酮对二甲基苯并蒽 (DMBA) 诱导的肝细胞氧化损伤有保护作用。DMBA 下调的过氧化氢酶和超氧化物歧化酶活性可被大豆苷元恢复。

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signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Katherine A Jackman et al.
Current medicinal chemistry, 14(26), 2824-2830 (2007-11-30)
Isoflavones are an important class of phytoestrogens that are found at extrememly high levels in soy. Up until recently, daidzein and genistein were considered to be the most important and hence most studied isoflavones, however more recently attention has shifted
Vera van der Velpen et al.
The Journal of nutrition, 143(6), 774-780 (2013-04-26)
Isoflavones (genistein, daidzein, and glycitein) are suggested to have benefits as well as risks for human health. Approximately one-third of the Western population is able to metabolize daidzein into the more potent metabolite equol. Having little endogenous estradiol, equol-producing postmenopausal
Ivonne M C M Rietjens et al.
Molecular nutrition & food research, 57(1), 100-113 (2012-11-24)
Isoflavones are phytoestrogens that have been linked to both beneficial as well as adverse effects in relation to cell proliferation and cancer risks. The present article presents an overview of these seemingly contradicting health effects and of mechanisms that could
M Uehara et al.
The Journal of steroid biochemistry and molecular biology, 72(5), 273-282 (2000-05-24)
A time-resolved fluoroimmunoassay (TR-FIA), with europium labeled phytoestrogens as tracers, was developed for the quantitative determination of enterolactone, genistein and daidzein in human urine. The aim was to create a method for the screening of large populations in order to
J W Lampe et al.
The American journal of clinical nutrition, 60(1), 122-128 (1994-07-01)
Lignans and isoflavonoid phytoestrogens, produced from plant precursors by colonic bacteria, may protect against certain cancers. We examined the effects of flaxseed consumption on urinary lignans and isoflavonoids. Eighteen women consumed their usual omnivorous diets for three menstrual cycles and

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