D2316
DAN/Fc Chimera human
>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
别名:
Differential Screening-selected Gene Aberrative in Neuroblastoma
biological source
human
recombinant
expressed in NSO cells
assay
>95% (SDS-PAGE)
form
lyophilized powder
potency
1.5-6 μg/mL ED50
mol wt
monomer calculated mol wt 44.3 kDa, 55-65 kDa by SDS-PAGE (reducing)
storage condition
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... NBL1(4681)
Biochem/physiol Actions
DAN, a member of the DAN family of secreted glycoproteins, is an antagonist for the TGF-β superfamily. DAN binds the TGF-β ligands and prevents their interactions with signaling receptor complexes.
Member of the DAN family of secreted glycoproteins; an antagonist for the TGF-β superfamily; binds the TGF-β ligands and prevents their interactions with signaling receptor complexes.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
Analysis Note
The biological activity is measured by its ability to inhibit BMP-4 activity in ATDC-5 cells.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
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