D3389
2′-Deoxycytidine 3′-monophosphate sodium salt
≥95%
别名:
3′-dCMP sodium salt
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关于此项目
经验公式（希尔记法）:
C9H14N3O7P · xNa+
化学文摘社编号:
分子量:
307.20 (free acid basis)
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
产品名称
2′-Deoxycytidine 3′-monophosphate sodium salt, ≥95%
SMILES string
[Na].NC1=NC(=O)N(C=C1)C2CC(OP(O)(O)=O)C(CO)O2
assay
≥95%
storage temp.
−20°C
Application
2′-Deoxycytidine 3′-monophosphate (3′-dCMP) and 3′-dCMPH are used as a model molecules to elucidate the mechanism(s) of the nascent stage of DNA strand breakage and to study nucleic acid base modifications by adduct formation.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Jiande Gu et al.
Journal of the American Chemical Society, 128(4), 1250-1252 (2006-01-26)
To elucidate the mechanism of the nascent stage of DNA strand breakage by low-energy electrons, theoretical investigations of electron attachment to nucleotides have been performed by the reliably calibrated B3LYP/DZP++ approach (Chem. Rev. 2002, 102, 231). The 2'-deoxycytidine-3'-monophosphate (3'-dCMPH) and
Jiande Gu et al.
Journal of the American Chemical Society, 128(29), 9322-9323 (2006-07-20)
A detailed understanding of DNA strand breaks induced by low energy electrons (LEE) is of crucial importance for the advancement of many areas of molecular biology and medicine. To elucidate the mechanism of DNA strand breaks by LEEs, theoretical investigations
F el Ghissassi et al.
Chemical research in toxicology, 8(2), 278-283 (1995-03-01)
Lipid peroxidation (LPO) products are known to interact with DNA, yielding several types of adduct with nucleobases. In this study, we demonstrate the formation of two ethenobase adducts, 1,N6-ethenoadenine and 3,N4-ethenocytosine, by reaction of LPO products with nucleic acid bases.
S F Liu et al.
Carcinogenesis, 9(8), 1401-1404 (1988-08-01)
In vitro reaction of DNA with styrene-7,8-oxide (styrene oxide) produced five adducts, as determined by 32P-postlabeling. When styrene oxide was reacted in vitro with deoxyribonucleotides, five adducts were observed from 2'-deoxyguanosine-3'-monophosphate, two from 2'-deoxyadenosine-3'-monophosphate, none from 2'-deoxythymidine-3-monophosphate or 2'-deoxycytidine-3'-monophosphate. Chromatographic
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