D4162
4,4′-二苯胺基-1,1′-联萘-5,5′-二磺酸 二钾盐
fluorescent probe
别名:
Bis-ANS
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关于此项目
经验公式（希尔记法）:
C32H22K2N2O6S2
化学文摘社编号:
分子量:
672.85
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5714637
InChI
1S/C32H24N2O6S2.2K/c35-41(36,37)29-15-7-13-25-23(17-19-27(31(25)29)33-21-9-3-1-4-10-21)24-18-20-28(34-22-11-5-2-6-12-22)32-26(24)14-8-16-30(32)42(38,39)40;;/h1-20,33-34H,(H,35,36,37)(H,38,39,40);;/q;2*+1/p-2
SMILES string
[K+].[K+].[O-]S(=O)(=O)c1cccc2c(ccc(Nc3ccccc3)c12)-c4ccc(Nc5ccccc5)c6c(cccc46)S([O-])(=O)=O
InChI key
VWLWTJHKQHRTNC-UHFFFAOYSA-L
assay
≥97% (HPLC)
form
powder
solubility
methanol with 1 M NH4OH: 5 mg/mL, clear
Quality Level
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Application
蛋白质的双功能荧光探针。
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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E Daniel et al.
Biochemistry, 5(6), 1893-1900 (1966-06-01)
Jamie R Johnston et al.
The Journal of biological chemistry, 294(52), 20054-20069 (2019-11-22)
Aberrant regulation of myocardial force production represents an early biomechanical defect associated with sarcomeric cardiomyopathies, but the molecular mechanisms remain poorly defined. Here, we evaluated the pathogenicity of a previously unreported sarcomeric gene variant identified in a pediatric patient with
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Acta neuropathologica communications, 6(1), 6-6 (2018-01-31)
Neurodegenerative diseases are linked to a systemic enzyme resistance of toxic aggregated molecules and their pathological consequences. This paper presents a unique phenomenon that Philodina acuticornis, a bdelloid rotifer, is able to catabolize different types of neurotoxic peptide and protein
Evelin Balazs et al.
IBRO reports, 9, 319-323 (2020-12-19)
Investigation of human neurodegeneration-related aggregates of beta-amyloid 1-42 (Aβ42) on bdelloid rotifers is a novel interdisciplinary approach in life sciences. We reapplied an organ size-based in vivo monitoring system, exploring the autocatabolism-related alterations evoked by Aβ42, in a glucose-supplemented starvation
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