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Merck
CN

D6071

Diphenylacetohydroxamic acid

≥98% (HPLC)

别名:

N-Hydroxy diphenylacetamide

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关于此项目

经验公式(希尔记法):
C14H13NO2
化学文摘社编号:
分子量:
227.26
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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InChI

1S/C14H13NO2/c16-14(15-17)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13,17H,(H,15,16)

SMILES string

ONC(=O)C(c1ccccc1)c2ccccc2

InChI key

OFSBBVCLWMCGNY-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

off-white to light tan

solubility

DMSO: >20 mg/mL

storage temp.

2-8°C

Biochem/physiol Actions

Diphenylacetohydroxamic acid is a class IIa selective histone deacetylase inhibitor.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Douglas D Lemon et al.
FEBS letters, 589(10), 1080-1088 (2015-03-31)
PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors

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