D6783
DL-二氢鞘氨醇
≥98%, synthetic
别名:
1,3-二羟基-2-氨基十八烷, DL-1,3-二羟基-2-氨基十八烷
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选择尺寸
关于此项目
经验公式（希尔记法）:
C18H39NO2
化学文摘社编号:
分子量:
301.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
236-933-7
MDL number:
InChI key
OTKJDMGTUTTYMP-UHFFFAOYSA-N
InChI
1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3
SMILES string
CCCCCCCCCCCCCCCC(O)C(N)CO
biological source
synthetic
assay
≥98%
form
solid
storage temp.
−20°C
General description
二氢鞘氨醇是皮肤脂质屏障的重要组成部分，可保护人体免受过多的水分流失。
Application
DL-二氢鞘氨醇已用于引发酿酒酵母中的热应激信号。
Biochem/physiol Actions
鞘氨醇的生物合成前体。
Other Notes
赤型和苏型异构体的混合物。标识在标签上的含量。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A Kawamura et al.
Bioorganic & medicinal chemistry, 4(7), 1035-1043 (1996-07-01)
We have developed a simple picomole (low nanogram) scale HPLC scheme which can separate all eight isomers of sphingosine and dihydrosphingosine thus leading to the identification of their relative and absolute configurations. The amino group of the sample is derivatized
Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics
vSkolova B, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(5), 824-834 (2017)
Sphingolipids Are Potential Heat Stress Signals inSaccharomyces
Dickson RC, et al.
The Journal of Biological Chemistry, 272(48), 30196-30200 (1997)
E M Raeder et al.
Blood, 93(2), 686-693 (1999-01-13)
In the present study, we investigated the mechanism by which sphingosine and its analogues, dihydrosphingosine and phytosphingosine, inhibit polymorphonuclear leukocyte (PMN) phagocytosis of IgG-opsonized erythrocytes (EIgG) and inhibit ERK1 and ERK2 phosphorylation. We used antibodies that recognized the phosphorylated forms
Lucila Gisele Pescio et al.
Journal of lipid research, 58(7), 1428-1438 (2017-05-19)
Ceramides (Cers) and complex sphingolipids with defined acyl chain lengths play important roles in numerous cell processes. Six Cer synthase (CerS) isoenzymes (CerS1-6) are the key enzymes responsible for the production of the diversity of molecular species. In this study
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