D7033
DL-threo-Dihydrosphingosine
≥98%
别名:
DL-threo-1,3-Dihydroxy-2-aminooctadecane
方案
≥98%
储存温度
−20°C
SMILES字符串
CCCCCCCCCCCCCCC[C@@](O)([H])[C@@]([H])(N)CO
InChI
1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18-/m0/s1
InChI key
OTKJDMGTUTTYMP-ROUUACIJSA-N
生化/生理作用
Sphingosine kinase inhibitor.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
G S Dbaibo et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(5), 1347-1351 (1995-02-28)
Ceramide, a lipid mediator, has been most closely associated with antiproliferative activities. In this study, we examine the mechanism by which ceramide induces growth suppression and the role of the retinoblastoma gene product (Rb) in this process. Withdrawal of serum
H Tokuda et al.
Journal of cellular biochemistry, 72(2), 262-268 (1999-02-18)
In osteoblast-like MC3T3-E1 cells, we have recently reported that sphingosine 1-phosphate among sphingomyelin metabolites acts as a second messenger for tumor necrosis factor-alpha (TNF)-induced interleukin-6 (IL-6) synthesis. In the present study, we investigated the effect of extracellular sphingomyelinase on IL-6
O Kozawa et al.
Journal of cellular biochemistry, 70(3), 338-345 (1998-08-26)
We previously reported that prostaglandin (PG)E1 and PGF2alpha induce the synthesis of interleukin-6 (IL-6) via activation of protein kinase (PK)A and PKC, respectively, in osteoblast-like MC3T3-E1 cells. In addition, we have shown that basic fibroblast growth factor (bFGF) elicits IL-6
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