D7690
Monoclonal Anti-DNA Ligase I antibody produced in mouse
~1 mg/mL, clone 1A9, purified immunoglobulin, buffered aqueous solution
产品名称
Monoclonal Anti-DNA Ligase I antibody produced in mouse, ~1 mg/mL, clone 1A9, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1A9, monoclonal
form
buffered aqueous solution
mol wt
antigen ~125 kDa
species reactivity
bovine, human
concentration
~1 mg/mL
technique(s)
direct ELISA: suitable
western blot: 1-5 μg/mL using HeLa or DiFi cells
isotype
IgG1
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... LIG1(3978)
Application
Monoclonal Anti-DNA Ligase I antibody produced in mouse is suitable for direct ELISA and western blot at a working concentration of 1-5μg/mL using HeLa or DiFi cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
DNA ligase I is composed of a 78kDa carboxyl-terminal catalytic domain and a 24kDa amino-terminal region.
Immunogen
bovine DNA ligase I.
Physical form
Solution in phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.
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存储类别
10 - Combustible liquids
法规信息
新产品
此项目有
V J Mackenney et al.
The Journal of biological chemistry, 272(17), 11550-11556 (1997-04-25)
The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is believed to be due to DNA ligase I. This enzyme is composed of a 78-kDa carboxyl-terminal catalytic domain and a 24-kDa amino-terminal region that is not
商品
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
DNA损伤和修复机制对于维持DNA完整性至关重要。细胞DNA的损伤与突变、癌症发展等有关。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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