D8183
Dihydro-β-erythroidine hydrobromide
别名:
3β-1,6-Didehydro-14,17-dihydro-3-methoxy-16(15H)-oxaerythrinan-15-one hydrobromide
InChI key
GFIGWAJEIMHJJB-LINSIKMZSA-N
InChI
1S/C16H21NO3.BrH/c1-19-13-3-2-12-5-7-17-6-4-11-10-20-15(18)8-14(11)16(12,17)9-13;/h2,13H,3-10H2,1H3;1H/t13-,16-;/m0./s1
SMILES string
Br.CO[C@H]1CC=C2CC[N@@H]3CCC4=C(CC(=O)OC4)[C@]23C1
Biochem/physiol Actions
Competitive nicotinic receptor antagonist
法规信息
新产品
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C Rapier et al.
Journal of neurochemistry, 54(3), 937-945 (1990-03-01)
Presynaptic nicotinic acetylcholine receptors on striatal nerve terminals modulate the release of dopamine. We have compared the effects of a number of nicotinic agonists and antagonists on a perfused synaptosome preparation preloaded with [3H]dopamine. (-)-Nicotine, acetylcholine, and the nicotinic agonists
Y T Wang et al.
Neuroscience, 40(3), 759-767 (1991-01-01)
The purpose of this study was to determine if ambigual oesophageal motoneurons of the rat possess functional nicotinic cholinoceptors. In urethane anaesthetized rats, acetylcholine (20-50 pmol) delivered micropneumophoretically from multibarrelled pipettes to the compact formation of the nucleus ambiguus produced
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