一般描述
Corning TransportoCells products are high performance mammalian cells in a convenient, cryopreserved format that transiently overexpress a single human SLC transporter protein. The frozen cells deliver robust data, while eliminating the time required to culture and maintain stable cell lines.
Culturing and maintaining stable transporter cell lines can be expensive and time-consuming. In addition, it can take a week or more to prepare cells for assaying. Corning TransportoCells products can be thawed, plated and assayed in just two days with high uptake ratios.
Culturing and maintaining stable transporter cell lines can be expensive and time-consuming. In addition, it can take a week or more to prepare cells for assaying. Corning TransportoCells products can be thawed, plated and assayed in just two days with high uptake ratios.
应用
Convenient and Cost-efficient
Corning TransportoCells products are a convenient, cost-efficient alternative to maintaining stable cell lines. They provide the utmost flexibility for experimental planning. The cells can be removed from storage one day and assayed the following day.
Robust and Validated
The model has been fully validated for substrate specificity, transporter kinetics, and inhibition profiles to ensure data are consistent with existing transporter cell models.
Supports Regulatory Recommendations
Corning TransportoCells products are a convenient, cost-efficient alternative to maintaining stable cell lines. They provide the utmost flexibility for experimental planning. The cells can be removed from storage one day and assayed the following day.
Corning TransportoCells products are a convenient, cost-efficient alternative to maintaining stable cell lines. They provide the utmost flexibility for experimental planning. The cells can be removed from storage one day and assayed the following day.
Robust and Validated
The model has been fully validated for substrate specificity, transporter kinetics, and inhibition profiles to ensure data are consistent with existing transporter cell models.
Supports Regulatory Recommendations
Corning TransportoCells products are a convenient, cost-efficient alternative to maintaining stable cell lines. They provide the utmost flexibility for experimental planning. The cells can be removed from storage one day and assayed the following day.
特点和优势
- Cryopreserved format provides flexibility for experimental planning.
- Cells are readily available, can be stored onsite and shipped globally.
- Cells can be thawed, plated and assayed in just two days.
- Robust results with uptake ratios ≥10 fold.
- Consistent with other mammalian cell-based models.
- One vial contains 10 million cells and supports one 24-well or one 96-well plate.
- Includes all current USFDA and European Medicines Agency (EMA)-recommended SLC drug transporters.
法律信息
Corning is a registered trademark of Corning, Inc.
TransportoCells is a trademark of Corning, Inc.
法规信息
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