Anti-Estrogen-Related Receptor β antibody produced in rabbit

synthetic peptide corresponding to the internal domain of human estrogen-related receptor β, conjugated to KLH. The immunizing peptide has 93% homology with the rat and mouse gene.

Anti-Estrogen-Related Receptor β antibody produced in rabbit was used for immunocytochemistry of neurons from mouse model of glaucoma at a working dilution of 1:500. It was also used for immunohistochemistry of mouse brain sections.

Estrogen-Related Receptors (ERR) are hormone receptors that bind estrogen response elements that in turn bind specific DNA sequences and regulate transcription. Three ERRs are known, alpha, beta and gamma, with highly conserved ligand and DNA binding sequences. ERRβ is selectively expressed in brain and is an important modulator of energy balance, food intake, neuropeptide levels and response to stress.

Solution in phosphate buffered saline, containing 0.1% sodium azide.

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