E0281
Anti-Estrogen-Related Receptor γ antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-ERRγ, Anti-NR3B3
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p)
Citations:
2
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
availability
not available in Japan
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 17 μg/mL using human breast tissue
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ESRRG(2104)
mouse ... Esrrg(26381)
rat ... Esrrg(360896)
Immunogen
synthetic peptide corresponding to the internal domain of human estrogen-related receptor γ conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.
Biochem/physiol Actions
Estrogen-Related Receptors (ERR) are hormone receptors that bind estrogen response elements that in turn bind specific DNA sequences and regulate transcription. Three ERRs are known, alpha, beta and gamma, with highly conserved ligand and DNA binding sequences. ERRγ is selectively expressed in brain and is an important modulator of energy balance, food intake, neuropeptide levels and response to stress.
Physical form
Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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相关内容
Instructions
Mardi S Byerly et al.
BMC physiology, 13, 10-10 (2013-09-24)
Estrogen-related receptors (ERRs) are orphan nuclear hormone receptors expressed in metabolically active tissues and modulate numerous homeostatic processes. ERRs do not bind the ligand estrogen, but they are able to bind the estrogen response element (ERE) embedded within the ERR
William A Alaynick
Mitochondrion, 8(4), 329-337 (2008-04-01)
Lipid metabolism is a continuum from emulsification and uptake of lipids in the intestine to cellular uptake and transport to compartments such as mitochondria. Whether fats are shuttled into lipid droplets in adipose tissue or oxidized in mitochondria and peroxisomes
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E0281-50UL | 04061835807536 |