E0514
E-64c
Calpain Inhibitor
别名:
(2S,3S)-trans-Epoxysuccinyl-
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关于此项目
经验公式（希尔记法）:
C15H26N2O5
化学文摘社编号:
分子量:
314.38
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
biological source
synthetic (organic)
assay
≥98% (HPLC)
form
powder
solubility
ethanol: 20 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(C)CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H]1O[C@@H]1C(O)=O
InChI
1S/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1
InChI key
SCMSYZJDIQPSDI-SRVKXCTJSA-N
Gene Information
human ... CAPN1(823)
Biochem/physiol Actions
Cysteine protease inhibitor; membrane-impermeable calpain inhibitor. Significantly reduces calpain-mediated depletion of microtubule-associated protein (MAP2) in an animal model of an ischemic brain.
Cysteine protease inhibitor; membrane-impermeable calpain inhibitor.
Other Notes
Synthetic analog of E-64
存储类别
13 - Non Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)