E1889
(+)-伪麻黄碱 盐酸盐
Sigma Reference Standard
别名:
(+)-ψ-麻黄碱 盐酸盐, (1S,2S)-2-甲氨基-1-苯丙醇 盐酸盐, d-伪麻黄碱 盐酸盐, d-异麻黄碱 盐酸盐
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关于此项目
线性分子式:
C6H5CH[CH(NHCH3)CH3]OH·HCl
化学文摘社编号:
分子量:
201.69
Beilstein:
3915112
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
包装
vial of 250 mg
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
185-188 °C (lit.)
包装形式
neat
SMILES字符串
Cl.CN[C@@H](C)[C@@H](O)c1ccccc1
InChI
1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10+;/m0./s1
InChI key
BALXUFOVQVENIU-KXNXZCPBSA-N
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应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
生化/生理作用
非选择性肾上腺素激动剂;减充血剂
包装
棕色螺纹盖样品瓶包装
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - STOT SE 3
靶器官
Central nervous system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Minjie Jiang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 974, 126-130 (2014-12-03)
A rapid, sensitive and selective high-performance liquid chromatography-tandem mass spectrometric method (HPLC-MS) has been developed and validated for the simultaneous determination of 14-thienyl methylene matrine (TMM) and matrine (MT) in rat plasma in the present study. The analytes were separated
Minjie Jiang et al.
PloS one, 10(2), e0116010-e0116010 (2015-02-26)
A rapid, sensitive and selective high-performance liquid chromatography-tandem mass spectrometric method (HPLC-MS) was developed and validated to determine the 14-(3-methylbenzyl)matrine (3MBM) and 14-(4-methylbenzyl)matrine (4MBM) levels in rat plasma in the present study. The analytes were separated using a C18 column
Sean Ekins et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17)
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify compounds
Nigel Greene et al.
Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18)
Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential
Zhichao Liu et al.
PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated
Chromatograms
application for HPLC
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