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Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human
Citations:
1
Technique(s):
western blot: 1:1,000-1:5,000
产品名称
Anti-EAPII (TTRAP) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~41 kDa by calculation
species reactivity
human
technique(s)
western blot: 1:1,000-1:5,000
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... TTRAP(51567)
Application
Anti-EAPII (TTRAP) antibody produced in rabbit is suitable for western blot analysis at a working dilution of 1:1000-1:5000.
Biochem/physiol Actions
Ets proteins are a family of conserved sequence specific DNA-binding proteins. They function as transcription factors with roles in differentiation, lymphoid cell development, invasiveness, and angiogenesis. ETS1-associated protein II (EAPII) interacts with ETS1 and other Ets proteins (ETS2 and FLI1). EAPII is mainly localized to the nucleus of mammalian cells. EAPII negatively modulates the transcriptional activity of ETS1. It reduces synergistic transactivation by ETS1 and AP-1. Re-expression of EAPII prevents the migration of epithelial cancer cells. It does not affect cell viability.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
peptide corresponding to the human EAPII (amino acids 11-28).
Physical form
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Huiping Pei et al.
Oncogene, 22(18), 2699-2709 (2003-05-14)
Ets proteins constitute a family of conserved sequence-specific DNA-binding proteins and function as transcription factors. ETS1 plays important roles in differentiation, lymphoid cell development, invasiveness and angiogenesis. Such diverse roles of ETS1 are likely to be dependent on its associated
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