Anti-Estrogen-Related Receptor α 1 antibody produced in rabbit

synthetic peptide M(1)SSQVVGIEPL­YIKAE(16) corresponding to amino acid residues 1-16 from human ERR1 protein.

Estrogen-Related Receptors (ERR) are hormone receptors that bind estrogen response elements that in turn bind specific DNA sequences and regulate transcription. Three ERRs are known, alpha, beta and gamma, with highly conserved ligand and DNA binding sequences. ERRα is selectively expressed in kidney, heart, cerebellum, intestine and skeletal muscle. It is an important modulator of energy balance, food intake, neuropeptide levels and response to stress.

Provided as ~100 μg of affinity purified antibody (1 mg/mL) in phosphate buffered saline containing 1 mg/mL bovine serum albumin and 0.05% sodium azide.

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