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Merck
CN

E3005

des-Tyr1-γ-Endorphin

≥97% (HPLC)

别名:

β-Lipotropin 62-77

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关于此项目

经验公式(希尔记法):
C74H122N18O25S
化学文摘社编号:
分子量:
1695.93
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C74H122N18O25S/c1-36(2)29-47(66(108)88-57(38(5)6)70(112)90-59(40(8)96)71(113)85-49(74(116)117)30-37(3)4)84-69(111)52-20-16-27-92(52)73(115)60(41(9)97)91-63(105)44(21-23-53(77)98)81-67(109)50(34-93)86-61(103)43(19-14-15-26-75)80-62(104)45(22-24-56(101)102)82-68(110)51(35-94)87-72(114)58(39(7)95)89-64(106)46(25-28-118-10)83-65(107)48(31-42-17-12-11-13-18-42)79-55(100)33-78-54(99)32-76/h11-13,17-18,36-41,43-52,57-60,93-97H,14-16,19-35,75-76H2,1-10H3,(H2,77,98)(H,78,99)(H,79,100)(H,80,104)(H,81,109)(H,82,110)(H,83,107)(H,84,111)(H,85,113)(H,86,103)(H,87,114)(H,88,108)(H,89,106)(H,90,112)(H,91,105)(H,101,102)(H,116,117)

SMILES string

CSCCC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCC(O)=O)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(O)=O

InChI key

YQEWLSJJOSZFHG-UHFFFAOYSA-N

assay

≥97% (HPLC)

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... POMC(5443)

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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G Chazot et al.
L'Encephale, 11(3), 113-116 (1985-05-01)
The chronobiological studies with melatonin constitute valid arguments to consider melatonin as a peripheral index of depressive disorders. In a group of patients with major depression, we reported a lowering of melatonin nocturnal plasma levels, associated with cortisol hypersecretion. A
D S Goldbloom
Canadian journal of psychiatry. Revue canadienne de psychiatrie, 29(4), 355-360 (1984-06-01)
In the past decade both basic and clinical research on endogenous opiates has involved many aspects of medicine. This review focuses on the clinical literature that relates physiology and pathophysiology of the endogenous opiates to schizophrenia. Three major investigative approaches
Effects of alpha-endorphin, beta-endorphin and (des-tyr1)-gamma-endorphin on alpha-MPT-induced cateholamine disappearance in discrete regions of the rat brain.
D H Versteeg et al.
Brain research, 179(1), 85-92 (1979-12-21)
F H Claas et al.
Immunogenetics, 22(4), 309-314 (1985-01-01)
Preincubation of lymphocytes with des-Tyr1-gamma-endorphin (DT gamma E) inhibits the reaction between some HLA alloantisera and their corresponding antigens. One HLA-A2-specific antiserum was found which could detect a subtype of the HLA-A2 antigen on DT gamma E-treated lymphocytes from some
Neuroleptic activity of the neuropeptide beta-LPH62-77 ([Des-Tyr1]gamma-endorphin; DT gamma E).
D De Wied et al.
European journal of pharmacology, 49(4), 427-436 (1978-06-15)

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