E3645
rac-2-Ethoxy-3-hexadecanamido-1-propylphosphocholine
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关于此项目
线性分子式:
C26H55O6N2P
化学文摘社编号:
分子量:
522.70
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
impurities
≤0.5 mol/mol (NH4)2CO3
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCCCC(=O)NCC(COP([O-])(=O)OCC[N+](C)(C)C)OCC
Gene Information
human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584)
Biochem/physiol Actions
Protein kinase C inhibitor.
法规信息
新产品
此项目有
M H Marx et al.
Journal of medicinal chemistry, 31(4), 858-863 (1988-04-01)
Previously unreported analogues of the synthetic antitumor phospholipid ET-18-OMe (1-octadecyl-2-methoxy-rac-glycero-3-phosphocholine), in which the 1-ether oxygen has been replaced by an amido group, have been prepared and evaluated for in vitro cytotoxic effects and for inhibition of protein kinase C. The
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the