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Merck
CN

E6386

Sigma-Aldrich

γ-Endorphin

≥95% (HPLC)

别名:

β-Lipotropin 61-77

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关于此项目

经验公式(希尔记法):
C83H131N19O27S
化学文摘社编号:
分子量:
1859.10
MDL编号:
UNSPSC代码:
12352200
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方案

≥95% (HPLC)

UniProt登记号

储存温度

−20°C

基因信息

human ... POMC(5443)

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Amino Acid Sequence

Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu

生化/生理作用

Opioid agonist that does not produce generalized rigidity or loss of tail pinch reflex when injected intraventricularly.

其他说明

β-Lipotropin fragment found in intermediate and anterior lobes of the pituitary

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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F Facchinetti et al.
Journal of endocrinological investigation, 12(10), 693-698 (1989-11-01)
Follicular fluid (FF) levels of immuno reactive beta-Endorphin (i.r. beta-EP), i.r. gamma-Endorphin (i.r. gamma-EP), i.r. alpha-melanocyte-stimulating hormone (i.r. alpha-MSH), androgens and estrogens were measured in 76 preovulatory follicles obtained, after gonadotropin stimulation from 19 women undergoing in vitro fertilization (IVF).
W R Van Furth et al.
European journal of pharmacology, 203(3), 413-416 (1991-10-22)
gamma-Type endorphins mimic neuroleptics in inducing a grasping response in rats. It was studied whether the haloperidol-induced grasping response was altered after blockade of gamma-type endorphin activity in the rat brain. To achieve this blockade rats were injected i.c.v. with
K Hagi et al.
Blood, 86(4), 1316-1321 (1995-08-15)
The present study was performed to investigate the effect of beta-endorphin on macrophage colony-stimulating factor (M-CSF)-induced differentiation of macrophages from bone marrow cells in a semisolid culture system. beta-endorphin increased the number of macrophage colonies when bone marrow cells were
Hari Kosanam et al.
Analytical biochemistry, 392(1), 83-89 (2009-06-03)
Quantification of alpha- and gamma-endorphins in rat brain using liquid chromatography-electrospray ionization-tandem mass spectrometry is described. [D-Ala(2)]-gamma-endorphin is used as an internal standard. The precursor-to-product ion MRM transitions for alpha-endorphin, gamma-endorphin, and [D-Ala(2)]-gamma-endorphin were m/z 873.6-->429.6; 929.6-->542.3; 936.6-->542.3, respectively. The
I Aebischer et al.
Experimental dermatology, 5(1), 38-44 (1996-02-01)
Corticotropin releasing factor, adrenocorticotropic hormone (ACTH) and alpha-melanocyte stimulating hormone either inhibit or enhance in a dose-dependent fashion an interleukin-4 (IL-4) driven human IgE synthesis in vitro. Here, we show that culture conditions strongly influence the earlier observed dose- and

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