assay
≥97% (HPLC)
storage temp.
−20°C
SMILES string
CCC(C)C(NC(=O)C(Cc1ccccc1)NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(N)=O
Biochem/physiol Actions
Tachykinin originally isolated from the salivary gland of octopus with structural homology to substance P; potent vasodilator and hypotensive agent; induces salivation and increases capillary permeability. Agonist at tachykinin NK-2/NK-3 receptors.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
C Makridis et al.
Journal of gastroenterology and hepatology, 14(5), 500-507 (1999-06-04)
Diarrhoea is an important feature of the carcinoid syndrome, and various agents which may be released from carcinoid tumours have been considered to contribute pathophysiologically. The aim of the present study was to determine luminal concentrations of possible chemical mediators
S Kar et al.
The Journal of comparative neurology, 354(2), 253-281 (1995-04-03)
A number of neuroactive peptides including calcitonin gene-related peptide (CGRP), substance P, neurokinin B, opioids, somatostatin (SRIF), galanin, neurotensin and vasoactive intestinal polypeptide (VIP) have been localized in adult rat spinal cord and are considered to participate either directly and/or
P Pompei et al.
Peptides, 14(1), 97-102 (1993-01-01)
The present study evaluated the sensitivity of spontaneously hypertensive (SHR) and of Wistar Kyoto (WKY) rats to the hypotensive effect of tachykinins (TKs). Eledoisin, substance P, and the NK-1-selective agonist [Sar9,Met(O2)11]substance P evoked a smaller hypotensive response in SHR than