InChI
1S/C6H20N2O12P4.H3N/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20;/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);1H3
InChI key
STNSYZSNIYTNMI-UHFFFAOYSA-N
Application
Used as a complex with radioactive samarium as a radiopharmaceutical in cancer research. Corrosion inhibitor.
Biochem/physiol Actions
EDTMP is nitrogenous, polyphosphonic acid chelator that complexes with various metal ions.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Sabyasachi Sarkar et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 821(1), 81-87 (2005-05-28)
A matrix developed from N,N,N',N'-ethylenediaminetetramethylenephosphonic acid-modified zirconia beads (further referred to as r_PEZ); 25-38 microm in diameter and with a pore size of 22+/-3 nm, was utilized for the separation of immunoglobulins (Igs). r_PEZ has been shown to bind to
K Schomäcker et al.
Nuklearmedizin. Nuclear medicine, 32(1), 23-26 (1993-02-01)
It is well known that after application of radioactive complexes for tumour diagnosis or therapy, such as 67Ga-citrate or radiolanthanide complexes (167Tm- or 169Yb-nitrilotriacetate, -citrate, -alpha-hydroxyisobutyrate, 90Y-citrate, etc.) activity is accumulated not only in the tumour but also in other
J E Bayouth et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 35(1), 63-69 (1994-01-01)
Palliation of bone pain in patients with cancer metastatic to bone is being evaluated in several cancer centers by the administration of the bone-seeking phosphonate ethylenediaminetetramethylenephosphonic acid (EDTMP) chelated with the beta particle-emitting radionuclide 153Sm. In this study, 153Sm-EDTMP was
Radionuclide targeting of bone metastases: which efficacy?
S Leyvraz et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 8(9), 1598-1599 (1990-09-01)
G J Beyer et al.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 19(2), 201-203 (1992-02-01)
The influence of the ligands ethylenediaminetetramethylene phosphonic acid (EDTMP) and citrate (CIT) on the biodistribution of radio-yttrium in rats bearing a DS-carcinosarcoma was compared. 88Y-EDTMP and 87Y-CIT were i.v. injected into the same animals. Faster blood clearance and higher renal
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