E9252
β-Estradiol 17-hemisuccinate
别名:
1,3,5(10)-Estratriene-3,17β-diol 17-hemisuccinate, 3,17β-Hydroxy-1,3,5(10)-estratriene 17-hemisuccinate
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关于此项目
经验公式（希尔记法）:
C22H28O5
化学文摘社编号:
分子量:
372.45
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Form:
powder
Assay:
≥98.00% (TLC)
InChI
1S/C22H28O5/c1-22-11-10-16-15-5-3-14(23)12-13(15)2-4-17(16)18(22)6-7-19(22)27-21(26)9-8-20(24)25/h3,5,12,16-19,23H,2,4,6-11H2,1H3,(H,24,25)/t16-,17-,18+,19+,22+/m1/s1
SMILES string
[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24)OC(=O)CCC(O)=O
InChI key
YJPIDPAGJSWWBE-FNIAAEIWSA-N
assay
≥98.00% (TLC)
form
powder
solubility
methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
K W Kan et al.
Calcified tissue international, 35(6), 740-744 (1983-09-01)
Using the dextran charcoal method, a specific steroid receptor for dexamethasone, but not 17 beta-estradiol or 17 alpha-methyltrienolone, was demonstrated in cytosol prepared from mid-gestation fetal calf growth cartilage. Zonal analysis of cytoplasmic receptor levels showed that tissue sections from
Does postmenopausal bone loss respond to estrogen replacement therapy independent of bone loss rate?
C Christiansen et al.
Calcified tissue international, 35(6), 720-722 (1983-09-01)
Bone loss in postmenopausal women can be treated by hormonal substitution therapy. We investigated whether rapid bone losers (as opposed to nonrapid losers) respond sufficiently to estrogen treatment. A sample of 88 early postmenopausal women was followed up for a
S S Smith et al.
Brain research, 422(1), 40-51 (1987-09-29)
The purpose of this study was to test whether 17 beta-estradiol (E2) could alter neuronal activity or responsiveness to iontophoretically applied amino acid neurotransmitters in an area not reported to contain classical E2 receptors. Such a region is the cerebellum
Hyun-Min Joo et al.
International immunopharmacology, 14(1), 39-46 (2012-06-28)
The anti-inflammatory effects of hydrogen peroxide-producing lactic acid bacteria (LAB) against Candida albicans-induced vulvovaginal candidiasis in β-estradiol-immunosuppressed mice were examined. Oral and intravaginal treatment with these LABs significantly decreased the level of viable C. albicans within the vaginal cavity as
Maia M Cherney et al.
Biochimica et biophysica acta, 1784(11), 1625-1632 (2008-07-01)
We have determined the X-ray crystal structure of the Mycobacterium tuberculosis (Mtb) gene product encoded by the open reading frame Rv0760c at 1.50 A resolution by single-wavelength anomalous dispersion (SAD) phasing of diffraction data from crystals of the selenomethionine-substituted protein.
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