E9386
5-Ethyl-2′-deoxyuridine
≥95% (HPLC), synthetic (organic), powder
别名:
EUdR, Edoxudine
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选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C11H16N2O5
化学文摘社编号:
分子量:
256.26
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
239-226-1
MDL number:
Assay:
≥95% (HPLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless to yellow
Storage temp.:
−20°C
产品名称
5-Ethyl-2′-deoxyuridine,
biological source
synthetic (organic)
Quality Segment
assay
≥95% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless to yellow
storage temp.
−20°C
SMILES string
CCC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O
InChI
1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)
InChI key
XACKNLSZYYIACO-UHFFFAOYSA-N
Biochem/physiol Actions
5-Ethyl-2′-deoxyuridine is an analog of pyrimidine, uridine. It is an effective antiviral agent and inhibits cell division in leukemic tumor cells. 5-Ethyl-2′-deoxyuridine interacts with 2′-deoxycytidine phosphate (dCTP) biosynthesis pathway to elicit antiproliferative effects.
5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels.
Other Notes
Homolog of thymidine
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)