Name: β-Estradiol 3-sulfate sodium salt
Brand: SIGMA

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About This Item

线性分子式:

C₁₈H₂₃O₅SNa

CAS Number:

4999-79-5

分子量:

374.43

MDL编号:

MFCD00056553

UNSPSC代码:

51111800

PubChem化学物质编号:

24894699

NACRES:

NA.77

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无菌性

non-sterile

质量水平

200

方案

≥93%

表单

powder

包含

~70% N-methyl-D-glucamine as stabilizer

溶解性

methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow

运输

ambient

储存温度

room temp

SMILES字符串

[Na].[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24

InChI

1S/C18H24O5S.Na.H/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;;/h3,5,10,14-17,19H,2,4,6-9H2,1H3,(H,20,21,22);;/t14-,15-,16+,17+,18+;;/m1../s1

InChI key

PYPVMTJYMKHIST-LBARCDFESA-N

一般描述

β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women.

应用

β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry.

生化/生理作用

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.