F107
氟桂嗪 二盐酸盐
别名:
1-[双(4-氟苯基)甲基]-4-(3-苯基-2-丙烯基)哌嗪 二盐酸盐
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关于此项目
经验公式（希尔记法）:
C26H26F2N2 · 2HCl
化学文摘社编号:
分子量:
477.42
EC Number:
250-216-6
UNSPSC Code:
12352203
PubChem Substance ID:
Beilstein/REAXYS Number:
4284243
MDL number:
InChI key
RXKMOPXNWTYEHI-RDRKJGRWSA-N
InChI
1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;
SMILES string
Cl[H].Cl[H].Fc1ccc(cc1)C(N2CCN(CC2)C\C=C\c3ccccc3)c4ccc(F)cc4
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
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Biochem/physiol Actions
阻断 T 型 Ca2+/Na+ 通道。
阻断 T 型 Ca2+/Na+ 通道；抑制嗜铬细胞中由 K+ 诱导的儿茶酚胺释放。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
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Revista de neurologia, 54(6), 332-336 (2012-03-10)
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Barbara Budzynska et al.
Behavioural brain research, 228(1), 144-150 (2011-12-20)
The motivational component of drug withdrawal may contribute to drug seeking and relapse through the negative reinforcement-related process; thus, it is important to understand the mechanisms that mediate affective withdrawal behaviors. The present study was undertaken to examine the calcium-dependent
R Aishworiya et al.
Annals of tropical paediatrics, 31(2), 149-152 (2011-05-18)
Alternating hemiplegia of childhood (AHC) is a rare neurological disorder which usually presents before 18 months of age and is characterised by recurrent alternating episodes of hemiparesis. A single effective treatment for this condition is yet to be established; flunarizine
Hunmin Kim et al.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 17(1), 45-49 (2012-11-01)
The purpose of this study was to compare the efficacy and tolerability of topiramate and flunarizine for the prophylaxis of pediatric migraines. A retrospective medical-record review of patients who underwent prophylaxis after receiving a diagnosis of migraine with aura and
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