F113
R(−)-氟苯丙胺 盐酸盐
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关于此项目
经验公式（希尔记法）:
C12H16F3N · HCl
化学文摘社编号:
分子量:
267.72
UNSPSC Code:
12352116
PubChem Substance ID:
MDL number:
drug control
USDEA Schedule IV
SMILES string
Cl.CCN[C@H](C)Cc1cccc(c1)C(F)(F)F
InChI
1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m1./s1
InChI key
ZXKXJHAOUFHNAS-SBSPUUFOSA-N
Biochem/physiol Actions
活性较低的对映体
Neurotoxic on prolonged administration or at high dosage; releases serotonin from axon terminals by a nonexocytotic mechanism; anorectic.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
此项目有
Recent studies in the clinical pharmacology of anorectic drugs.
Silverstone, et al.
Recent Adv. Obes. Res., 5, 285-285 (1986)
Re: Estimate of deaths due to valvular insufficiency attributable to the use of benfluorex in France.
Nicolas Deltour et al.
Pharmacoepidemiology and drug safety, 21(6), 584-585 (2012-04-21)
Christophe Tribouilloy et al.
Circulation, 126(24), 2852-2858 (2012-11-13)
Benfluorex was withdrawn from European markets in June 2010 after reports of an association with heart valve lesions. The link between benfluorex and valve regurgitations was based on small observational studies and retrospective estimations. We therefore designed an echocardiography-based multicenter