F1305
Anti-FEN-1 (C-terminal) antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-Flap endonuclease, Anti-Flap structure-specific endonuclease 1
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 45 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
immunoprecipitation (IP): 2-4 μg using HEK 293T cell lysates, indirect immunofluorescence: 5-10 μg/mL using paraformaldehyde-fixed HEK 293T cells, western blot: 0.5-1 μg/mL using K562 cell lysates
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... FEN1(2237)
mouse ... Fen1(14156)
rat ... Fen1(84490)
General description
FEN-1 (C-terminal) encodes a protein that removes 5′ overhanging flaps in DNA repair and processes the 5′ ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch b
Immunogen
synthetic peptide corresponding to amino acids 367-380 of human FEN-1, conjugated to KLH via an N-terminal added cysteine residue. The corresponding sequence in rat and mouse differs by one and two amino acids, respectively.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
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