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Merck
CN

F1305

Sigma-Aldrich

Anti-FEN-1 (C-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

别名:

Anti-Flap endonuclease, Anti-Flap structure-specific endonuclease 1

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MDL编号:
UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen 45 kDa

种属反应性

human

浓度

~1 mg/mL

技术

immunoprecipitation (IP): 2-4 μg using HEK 293T cell lysates
indirect immunofluorescence: 5-10 μg/mL using paraformaldehyde-fixed HEK 293T cells
western blot: 0.5-1 μg/mL using K562 cell lysates

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... FEN1(2237)
mouse ... Fen1(14156)
rat ... Fen1(84490)

一般描述

FEN-1 (C-terminal) encodes a protein that removes 5′ overhanging flaps in DNA repair and processes the 5′ ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch b

免疫原

synthetic peptide corresponding to amino acids 367-380 of human FEN-1, conjugated to KLH via an N-terminal added cysteine residue. The corresponding sequence in rat and mouse differs by one and two amino acids, respectively.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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