Anti-PFKFB3 (472-484) antibody produced in rabbit

synthetic peptide corresponding to amino acids 472-484 of human PFKFB3.

Anti-PFKFB3 (472-484) antibody is suitable for western blot analysis at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

PFKFB3 is ubiquitously present in nucleus of proliferating tissues, transformed cells, in various solid tumours and astrocytomas. In mammals, four types of PFKFB genes have been identified such as PFKFB1, PFKFB2, PFKFB3 and PFKFB4 which encode for the different PFK-2/FBPase-2 isoenzymes. Their characterization depends on the tissue expression pattern. PFKFB3 is associated with cell proliferation in carbohydrate metabolism.It has the highest PFK-2/FBPase-2 activity ratio.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

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