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经验公式(希尔记法):
C19H18NFO3
化学文摘社编号:
分子量:
327.35
UNSPSC Code:
12161501
PubChem Substance ID:
MDL number:
InChI
1S/C19H18FNO3/c1-12-16(10-19(22)23)17-9-15(24-2)7-8-18(17)21(12)11-13-3-5-14(20)6-4-13/h3-9H,10-11H2,1-2H3,(H,22,23)
SMILES string
COc1ccc2n(Cc3ccc(F)cc3)c(C)c(CC(O)=O)c2c1
InChI key
DIGWWZCEDODOMZ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
color
off-white
mp
167-169 °C
solubility
H2O: ≥18 mg/mL
storage temp.
2-8°C
Gene Information
human ... ABCC1(4363)
Biochem/physiol Actions
Putative inhibitor of multidrug resistance-associated protein 1 (MRP1).
Other Notes
N-benzoyl analog of indomethacin
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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Protein-based drug transporters are expressed in Sf9 cells. Understanding the specific mechanisms of tumor cell transporters is an essential aspect of chemotherapeutic drug design.
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