F4429
FAUC 213
≥98% (HPLC), solid
别名:
2-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine
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关于此项目
经验公式（希尔记法）:
C18H19ClN4
化学文摘社编号:
分子量:
326.82
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
eCl@ss:
32100101
Assay:
≥98% (HPLC)
Form:
solid
assay
≥98% (HPLC)
form
solid
color
white
solubility
DMSO: ~24 mg/mL (with warming up to 60 °C), H2O: insoluble
storage temp.
2-8°C
SMILES string
Clc1ccc(cc1)N2CCN(CC2)Cc3cc4ccccn4n3
InChI
1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
InChI key
DTRXURJDKOYCCD-UHFFFAOYSA-N
Gene Information
human ... DRD2(1813), DRD3(1814), DRD4(1815)
Application
FAUC 213 has been used as a selective dopamine receptor D4-R antagonist:
- to test its effect on the expression of luteinizing hormone in eel pituitary primary cell culture
- to test its effect on bupropion induced hypophagia and locomotion in rats
- to test its modulatory effects on rat basolateral amygdala in the presence of dopamine
警示词
Warning
危险代码
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
存储类别
11 - Combustible Solids
WGK
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
dust mask type N95 (US), Eyeshields, Gloves