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About This Item
经验公式(希尔记法):
C18H19ClN4
CAS Number:
分子量:
326.82
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
solid
颜色
white
溶解性
DMSO: ~24 mg/mL (with warming up to 60 °C)
H2O: insoluble
储存温度
2-8°C
SMILES字符串
Clc1ccc(cc1)N2CCN(CC2)Cc3cc4ccccn4n3
InChI
1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
InChI key
DTRXURJDKOYCCD-UHFFFAOYSA-N
基因信息
human ... DRD2(1813), DRD3(1814), DRD4(1815)
应用
FAUC 213 has been used as a selective dopamine receptor D4-R antagonist:
- to test its effect on the expression of luteinizing hormone in eel pituitary primary cell culture
- to test its effect on bupropion induced hypophagia and locomotion in rats
- to test its modulatory effects on rat basolateral amygdala in the presence of dopamine
生化/生理作用
FAUC 213 displays antipsychotic properties and may be of use in studies related to behavioral neurobiology and neurochemistry.
Highly selective D4 dopamine receptor full antagonist
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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