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About This Item
经验公式（希尔记法）:
C17H18F3N3O3
CAS Number:
分子量:
369.34
MDL编号:
UNSPSC代码:
51102829
PubChem化学物质编号:
NACRES:
NA.85
方案
≥98% (HPLC)
表单
solid
颜色
white to off-white
溶解性
0.1 M NaOH: 10 mg/mL
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
mycoplasma
作用机制
DNA synthesis | interferes
enzyme | inhibits
储存温度
−20°C
SMILES字符串
CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN(CCF)c3c2F)C(O)=O
InChI
1S/C17H18F3N3O3/c1-21-4-6-22(7-5-21)15-12(19)8-10-14(13(15)20)23(3-2-18)9-11(16(10)24)17(25)26/h8-9H,2-7H2,1H3,(H,25,26)
InChI key
XBJBPGROQZJDOJ-UHFFFAOYSA-N
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应用
Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It is used in pharmacokinetic studies and is used to study the treatment of intra-abdominal abscesses and travellers′ diarrhea.
生化/生理作用
Fleroxacin is a synthetic trifluorinated quinolone with antimicrobial activity against a variety of pathogens, including mycobacteria, mycoplasmas, chlamydiae, and legionellae. It strongly inhibits the DNA-supercoiling activity of DNA gyrase and DNA topoisomerase 2, which results in cell death.
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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