生物来源
wheat (gluten)
表单
lyophilized powder
颜色
white
溶解性
water, double-distilled: soluble
储存温度
−20°C
Amino Acid Sequence
H-Tyr-Pro-Gln-Pro-Gln-Pro-Phe-OH
一般描述
Gliadorphin-7 is a peptide corresponding to amino-acids 43-49 of gliadin, a component of the gluten protein. Gliadorphin-7 is an opoid peptide formed in the body by the digestion of the gliadin. Accumulation of this peptide was found in autism, schizophrenia and cealic disease possibly due to improper proteolysis.
Gliadorphin-7 is one of the seven most commonly known gluten exorphins (GEs), which is a peptide derived from gliadin. Gliadin is a component of gluten found in wheat. Gliadorphin-7 peptide is produced upon the digestion of wheat glutens, and has an opioid-like activity. It is composed of Tyr-Pro-Gln-Pro-Gln-Pro-Phe, Gd-7.
生化/生理作用
Gliadorphin-7 can reach regions in brain by diffusion circumventricular organs. Studies in rats show that gliadorphin-7 (GD-7) infusion results in high presence of this peptide in both geniculate nuclei (GN) and the alveus hippocampus.
外形
Lyophilized from 0.1% aqueous TFA
其他说明
Lyophilized from 0.1% TFA in H2O
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Zhongjie Sun et al.
Peptides, 24(2), 321-323 (2003-04-02)
This paper discusses the effects of gliadorphin-7 (GD-7) infusion in rats and contrasts them with those of beta-casomorphin-7 (betaC-7). Both induce FLI in a dose related fashion. Very strong expression in both geniculate nuclei (GN) and the alveus hippocampus follow
Release of wheat gluten exorphins A5 and C5 during in vitro gastrointestinal digestion of bread and pasta and their absorption through an in vitro model of intestinal epithelium.
Stuknyte, M et al
Food Research International, 72, 208-214 (2015)
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