G6171
Anti-Glial Fibrillary Acidic Protein Antibody
mouse monoclonal, G-A-5
别名:
抗 GFAP
登录 查看组织和合同定价。
选择尺寸
关于此项目
Conjugate:
unconjugated
Clone:
G-A-5, monoclonal
Application:
ICC, IF, IHC, WB
Citations:
102
产品名称
抗- 胶质纤维酸性蛋白抗体，小鼠单克隆, clone G-A-5, purified from hybridoma cell culture
biological source
mouse
conjugate
unconjugated
antibody form
purified from hybridoma cell culture, purified immunoglobulin
antibody product type
primary antibodies
clone
G-A-5, monoclonal
form
buffered aqueous solution
mol wt
antigen ~50 kDa
species reactivity
rat, human, pig
concentration
~1.0 mg/mL
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, indirect immunofluorescence: 2.5-5 μg/mL using alcohol-fixed sections of rat brain/cerebellum., western blot: suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GFAP(2670)
mouse ... Gfap(14580)
pig ... GFAP(396562)
rat ... Gfap(24387)
正在寻找类似产品? 访问 产品对比指南
General description
神经胶质原纤维酸性蛋白（GFAP）是存在于星形胶质细胞中的中间丝，以10种不同的亚型进行表达。它由N端头部、中心杆和C端尾部结构域组成。GFAP位于人类染色体17q21.33。
Immunogen
纯化的猪脊髓 GFAP。
Application
神经胶质纤维酸性蛋白单克隆抗体适用于蛋白印迹和间接免疫荧光（2.5-5 μg/mL，使用酒精固定的大鼠脑/小脑切片）。该抗体还可用于免疫印迹（约50 kDa）、免疫组化（多聚甲醛固定的兔脑冷冻切片）和免疫细胞化学。
神经胶质纤维酸性蛋白抗体（小鼠单克隆抗体）可用于免疫细胞化学和免疫荧光。
Biochem/physiol Actions
神经胶质纤维酸性蛋白或GFAP组装与神经胶质结构的有丝分裂重塑有关。GFAP基因突变与亚历山大病有关。
神经胶质纤维酸性蛋白（GFAP）基因位点的微缺失与儿童智力残疾和面部畸形有关。GFAP水平升高与急性脑出血有关。
Physical form
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Identification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation
Ito K, et al.
Scientific Reports, 6, 23903-23903 (2016)
M Inagaki et al.
Brain pathology (Zurich, Switzerland), 4(3), 239-243 (1994-07-01)
Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) protein of astroglia, and belongs to the type III subclass of IF proteins. IF proteins are composed of an amino-terminal HEAD domain, a central ROD domain and a carboxyterminal TAIL
Plasma glial fibrillary acidic protein in the differential diagnosis of intracerebral hemorrhage
Katsanos AH, et al.
Stroke, 48(9), 2586 -22588 (2017)
Novel organotypic in vitro slice culture model for intraventricular hemorrhage of premature infants.
Govindaiah Vinukonda et al.
Journal of neuroscience research, 90(11), 2173-2182 (2012-07-19)
Mechanisms of brain injury in intraventricular hemorrhage (IVH) of premature infants are elusive, and no therapeutic strategy exists to prevent brain damage in these infants. Therefore, we developed an in vitro organotypic forebrain slice culture model to advance mechanistic studies
Seila Fernandez-Fernandez et al.
Redox biology, 19, 52-61 (2018-08-15)
Loss of brain glutathione has been associated with cognitive decline and neuronal death during aging and neurodegenerative diseases. However, whether decreased glutathione precedes or follows neuronal dysfunction has not been unambiguously elucidated. Previous attempts to address this issue were approached
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持