生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
包含
0.02% sodium azide
1% bovine serum albumin
种属反应性
rat
技术
immunohistochemistry: suitable
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
rat ... Slc6a13(171163)
免疫原
synthetic peptide corresponding to the C-terminal domain (amino acids 594-602) of rat GAT-2.
应用
Anti-GABA Transporter GAT-2 antibody produced in rabbit is suitable for immunohistochemistry.
生化/生理作用
GAT-2 is a transporter for the selective uptake of γ-Aminobutyric acid (GABA). It belongs to a family of Na+ and Cl- co-dependent transporters, which include GAT-1, GAT-3 and BGT-1 transporters. These transporters have a molar mass of 67kDa each and contain 12 transmembrane regions. GABA is the major inhibitory neurotransmitter in the CNS and a neuromodulator in certain peripheral tissues.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
13 - Non Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
B I Kanner
The Journal of experimental biology, 196, 237-249 (1994-11-01)
The removal of neurotransmitters by their transporters--located in the plasma membranes of nerve terminals and glial cells--plays an important role in the termination of synaptic transmission. In the last 3 years, many neurotransmitter transporters have been cloned. Structurally and functionally
L A Borden
Neurochemistry international, 29(4), 335-356 (1996-10-01)
gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain. GABA is cleared from the synaptic cleft by specific, high-affinity, sodium- and chloride-dependent transporters, which are thought to be located on presynaptic terminals and surrounding glial cells. While
gamma-Aminobutyric acid outside the mammalian brain.
S L Erdö et al.
Journal of neurochemistry, 54(2), 363-372 (1990-02-01)
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