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Merck
CN

G7903

Glycophorin Predominantly glycophorin A 来源于 MM 型血液

lyophilized powder

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352202
MDL number:
Form:
lyophilized powder
Biological source:
human blood (type MN)
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biological source

human blood (type MN)

form

lyophilized powder

concentration

20-40% (Lowry)

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... GYPA(2993)

General description

Glycophorin A (GpA) is an important sialoglycoprotein on human red cells. It is one of the best characterized mammalian integral membrane proteins, containing three distinct domains. A large hydrophilic portion carries the NH2-terminal and is positioned on the external surface of the red cell, and the COOH-terminal is found in the cytoplasm. A hydrophobic segment of 23 amino acids (embedded within the lipid bilayer ) connects these two hydrophilic sequences.

Application

Glycophorin A was used to study the Plasmodium falciparum erythrocyte-binding antigen-175 (EBA175)-glycophorin-A interaction.

Biochem/physiol Actions

It is a membrane glycoprotein with several isoforms that interact with other membrane proteins to confer shape and antigenicity to erythrocytes.
A membrane glycoprotein with several isoforms that interact with other membrane proteins to confer shape and antigenicity to erythrocytes.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Lot/Batch Number

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Glycophorin A as an erythroid marker in normal and malignant hematopoiesis.
L C Andersson et al.
Haematology and blood transfusion, 26, 338-344 (1981-01-01)
Bishwanath Kumar Chourasia et al.
Infection and immunity, 88(2) (2019-11-13)
Cytoadherence-linked asexual gene 9 (Clag9), a conserved Plasmodium protein expressed during the asexual blood stages, is involved in the cytoadherence of infected red blood cells (RBCs) to the endothelial lining of blood vessels. Here, we show that Plasmodium falciparum Clag9



全球贸易项目编号

货号GTIN
G7903-1MG04061826738689
G7903-.5MG04061833643594