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Merck
CN

G8148

Gly-Arg-p-nitroanilide dihydrochloride

unokinase and plasmin substrate

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经验公式(希尔记法):
C14H21N7O4 · 2HCl
化学文摘社编号:
分子量:
424.28
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
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InChI

1S/C14H21N7O4.ClH/c15-8-12(22)20-11(2-1-7-18-14(16)17)13(23)19-9-3-5-10(6-4-9)21(24)25;/h3-6,11H,1-2,7-8,15H2,(H,19,23)(H,20,22)(H4,16,17,18);1H

SMILES string

Cl.NCC(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc(cc1)N(=O)=O

InChI key

MGFMNXNZZCRYAQ-UHFFFAOYSA-N

assay

≥98% (TLC)

form

powder

solubility

methanol: 20 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

General description

Substrate for plasmin and urokinase

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

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Flourogenic peptide amide substrates for the estimation of plasminogen activators and plasmin.
W Nieuwenhuizen et al.
Analytical biochemistry, 83(1), 143-148 (1977-11-01)
Thiago P Nascimento et al.
Anais da Academia Brasileira de Ciencias, 92(4), e20200882-e20200882 (2020-12-10)
The industrial demand for proteolytic enzymes is stimulating the search for new enzyme sources. Fungal enzymes are preferred over bacterial enzymes, and more effective and easier to extract. The aim of this work was to evaluate the potential of protease
Thiago Pajeú Nascimento et al.
Bioprocess and biosystems engineering, 40(8), 1209-1219 (2017-05-14)
Fibrinolytic proteases are enzymes that degrade fibrin. They provide a promising alternative to existing drugs for thrombolytic therapy. A protease isolated from the filamentous fungus Mucor subtilissimus UCP 1262 was purified in three steps by ammonium sulfate fractionation, ion exchange
Ning Luan et al.
Thrombosis and haemostasis, 117(6), 1031-1039 (2017-03-10)
The repugnatorial glands of millipedes release various defensive chemical secretions. Although varieties of such defensive secretions have been studied, none of them is protein or peptide. Herein, a novel factor Xa (FXa) inhibitor named joannsin was identified and characterised from repugnatorial glands

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