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Specific activity:
≥250 units/mg protein
Biological source:
Bacillus sp. (B. stearothermophilus)
biological source
Bacillus sp. (B. stearothermophilus)
form
lyophilized powder
specific activity
≥250 units/mg protein
composition
Protein, ≥60% biuret
shipped in
dry ice
storage temp.
−20°C
Quality Level
Physical form
含 Tris 缓冲盐的冻干粉
Other Notes
在pH 9.0、30 °C条件下,一个单位每分钟可将1.0 μM D-葡萄糖磷酸化为6-磷酸D-葡萄糖。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
David Callejas et al.
Diabetes, 62(5), 1718-1729 (2013-02-05)
Diabetes is associated with severe secondary complications, largely caused by poor glycemic control. Treatment with exogenous insulin fails to prevent these complications completely, leading to significant morbidity and mortality. We previously demonstrated that it is possible to generate a "glucose
Lei Zhang et al.
European journal of medicinal chemistry, 58, 624-639 (2012-11-28)
Dual-target-directed agents simultaneously inhibiting glycogen phosphorylase (GP) and activating glucokinase (GK) could decelerate the inflow of glucose from glycogenolysis and accelerate the outflow of glucose in the liver, therefore allow for a better control over hyperglycaemia in a synergetic manner.
Joeli Marrero et al.
PLoS pathogens, 9(1), e1003116-e1003116 (2013-01-18)
Mycobacterium tuberculosis (Mtb) is thought to preferentially rely on fatty acid metabolism to both establish and maintain chronic infections. Its metabolic network, however, allows efficient co-catabolism of multiple carbon substrates. To gain insight into the importance of carbohydrate substrates for
Property-based design in the optimisation of benzamide glucokinase activators: from hit to clinic.
Darren McKerrecher et al.
Progress in medicinal chemistry, 52, 1-43 (2013-02-07)
Päivi J Miettinen et al.
Duodecim; laaketieteellinen aikakauskirja, 128(19), 1989-1998 (2012-11-20)
MODY (Maturity-Onset Diabetes of the Young) is a group of monogenic disorders characterized by autosomally dominantly inherited diabetes or hyperglycemia typically detected during adolescence or young adulthood. Usually there is at least one person in the family having developed the
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QC Methods
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