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Merck
CN

G8887

葡萄糖激酶 来源于嗜热脂肪芽胞杆菌

lyophilized powder, ≥250 units/mg protein

别名:

ATP:D-葡萄糖-6-磷酸转移酶

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352204
MDL number:
Specific activity:
≥250 units/mg protein
Biological source:
Bacillus sp. (B. stearothermophilus)
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biological source

Bacillus sp. (B. stearothermophilus)

form

lyophilized powder

specific activity

≥250 units/mg protein

composition

Protein, ≥60% biuret

shipped in

dry ice

storage temp.

−20°C

Quality Level

Physical form

含 Tris 缓冲盐的冻干粉

Other Notes

在pH 9.0、30 °C条件下,一个单位每分钟可将1.0 μM D-葡萄糖磷酸化为6-磷酸D-葡萄糖。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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David Callejas et al.
Diabetes, 62(5), 1718-1729 (2013-02-05)
Diabetes is associated with severe secondary complications, largely caused by poor glycemic control. Treatment with exogenous insulin fails to prevent these complications completely, leading to significant morbidity and mortality. We previously demonstrated that it is possible to generate a "glucose
Lei Zhang et al.
European journal of medicinal chemistry, 58, 624-639 (2012-11-28)
Dual-target-directed agents simultaneously inhibiting glycogen phosphorylase (GP) and activating glucokinase (GK) could decelerate the inflow of glucose from glycogenolysis and accelerate the outflow of glucose in the liver, therefore allow for a better control over hyperglycaemia in a synergetic manner.
Joeli Marrero et al.
PLoS pathogens, 9(1), e1003116-e1003116 (2013-01-18)
Mycobacterium tuberculosis (Mtb) is thought to preferentially rely on fatty acid metabolism to both establish and maintain chronic infections. Its metabolic network, however, allows efficient co-catabolism of multiple carbon substrates. To gain insight into the importance of carbohydrate substrates for
Property-based design in the optimisation of benzamide glucokinase activators: from hit to clinic.
Darren McKerrecher et al.
Progress in medicinal chemistry, 52, 1-43 (2013-02-07)
Päivi J Miettinen et al.
Duodecim; laaketieteellinen aikakauskirja, 128(19), 1989-1998 (2012-11-20)
MODY (Maturity-Onset Diabetes of the Young) is a group of monogenic disorders characterized by autosomally dominantly inherited diabetes or hyperglycemia typically detected during adolescence or young adulthood. Usually there is at least one person in the family having developed the

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