G9144
抗醇溶蛋白（小麦） 兔抗
fractionated antiserum, buffered aqueous solution
别名:
抗醇溶蛋白（小麦）
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
DB, ELISA (i)
Citations:
10
biological source
rabbit
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
wheat
technique(s)
dot blot: 1:1,500, indirect ELISA: 1:5,000
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
wheat ... LOC543191(543191), LOC543191(543191), Loc543191(543191)
General description
麦胶蛋白是小麦及其他谷物中存在的蛋白质。T细胞识别麦胶蛋白抗原表位并激活先天性免疫应答，类似于T细胞识别麦胶蛋白表位并激活先天免疫应答，类似于对病原体的反应。这种反应在乳糜泻病中更为强烈，其中针对麦胶蛋白应答产生的肠源性T细胞会导致小肠损伤。因此，患有乳糜泻或谷蛋白敏感性疾病的患者应避免食用会产生麦胶蛋白的食物
麦胶蛋白是小麦面筋的重要组成部分。它由单链多肽组成，其分子量为25−100 kDa。它与分子内二硫键有关。
Immunogen
天然和热处理的小麦醇溶蛋白
Application
兔源抗麦胶蛋白（小麦）抗体可用于免疫印迹和酶联免疫吸附测定(ELISA)。
Biochem/physiol Actions
醇溶蛋白是一类含有谷氨酰胺的醇溶性蛋白质，来自于小麦和黑麦麦麸，又称为谷醇溶蛋白。这些蛋白质与人乳糜泻和谷蛋白敏感性肠病的有害作用有关，可引起小肠粘膜的特征性改变。在这种情况下，通常建议严格遵守无麸质饮食。
兔抗醇溶蛋白显示对天然小麦麦胶蛋白的特异性。
Physical form
溶于含有15 mM叠氮化钠的0.01 M磷酸盐缓冲液（pH 7.4）
Disclaimer
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Eduardo Garcia-Calvo et al.
Foods (Basel, Switzerland), 10(1) (2021-01-06)
Gluten is the ethanol-soluble protein fraction of cereal endosperms like wheat, rye, and barley. It is widely used in the food industry because of the physical-chemical properties it gives to dough. Nevertheless, there are some gluten-related diseases that are presenting
Determination of Prolamins in Beers by ELISA and SDS-PAGE
Kanerva P, et al.
Journal of the Institute of Brewing, 111(1), 61-64 (2005)
Luigi Maiuri et al.
Lancet (London, England), 362(9377), 30-37 (2003-07-11)
The adaptive immune system is central to the development of coeliac disease. Adaptive immune responses are, however, controlled by a preceding activation of the innate immune system. We investigated whether gliadin, a protein present in wheat flour, could activate an
Tobias L Freitag et al.
Gastroenterology, 158(6), 1667-1681 (2020-02-08)
Celiac disease could be treated, and potentially cured, by restoring T-cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged 500-nm poly(lactide-co-glycolide) nanoparticles encapsulating gliadin protein (TIMP-GLIA) in 3 mouse models of celiac disease. Uptake of these
The Level of Expression of Thioredoxin is Linked to Fundamental Properties and Applications of Wheat Seeds
Li YC, et al.
Molecular plant, 2(3), 430-441 (2009)
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