G9502
Guanylyl(3′→5′)uridine ammonium salt
别名:
GpU
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关于此项目
线性分子式:
C19H24N7O13P · NH3
化学文摘社编号:
分子量:
606.44
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
form
solid
storage temp.
−20°C
SMILES string
N.NC1=NC(=O)c2ncn(C3OC(CO)C(OP(O)(=O)OCC4OC(C(O)C4O)N5C=CC(=O)NC5=O)C3O)c2N1
InChI
1S/C19H24N7O13P.H3N/c20-18-23-14-9(15(32)24-18)21-5-26(14)17-12(31)13(6(3-27)37-17)39-40(34,35)36-4-7-10(29)11(30)16(38-7)25-2-1-8(28)22-19(25)33;/h1-2,5-7,10-13,16-17,27,29-31H,3-4H2,(H,34,35)(H,22,28,33)(H3,20,23,24,32);1H3
InChI key
BBBUJXLTQPKTLN-UHFFFAOYSA-N
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Hande Boyaci et al.
Nature, 565(7739), 382-385 (2019-01-11)
A key regulated step of transcription is promoter melting by RNA polymerase (RNAP) to form the open promoter complex1-3. To generate the open complex, the conserved catalytic core of the RNAP combines with initiation factors to locate promoter DNA, unwind
James Chen et al.
Molecular cell, 68(2), 388-397 (2017-10-11)
Noncoding RNAs (ncRNAs) regulate gene expression in all organisms. Bacterial 6S RNAs globally regulate transcription by binding RNA polymerase (RNAP) holoenzyme and competing with promoter DNA. Escherichia coli (Eco) 6S RNA interacts specifically with the housekeeping σ
Alena Kroupova et al.
Nucleic acids research, 47(2), 1030-1042 (2018-11-22)
Non-templated 3'-uridylation of RNAs has emerged as an important mechanism for regulating the processing, stability and biological function of eukaryotic transcripts. In Drosophila, oligouridine tailing by the terminal uridylyl transferase (TUTase) Tailor of numerous RNAs induces their degradation by the
Elizabeth Davis et al.
Nucleic acids research, 43(1), 433-445 (2014-12-17)
Escherichia coli has served as the archetypal organism on which the overwhelming majority of biochemical characterizations of bacterial RNA polymerase (RNAP) have been focused; the properties of E. coli RNAP have been accepted as generally representative for all bacterial RNAPs.
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