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Merck
CN

G9512

Gly-Phe β-naphthylamide

crystalline

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关于此项目

经验公式(希尔记法):
C21H21N3O2
化学文摘社编号:
分子量:
347.41
UNSPSC Code:
12352204
PubChem Substance ID:
MDL number:
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form

crystalline

storage temp.

−20°C

SMILES string

NCC(N[C@@H](CC1=CC=CC=C1)C(NC2=CC3=CC=CC=C3C=C2)=O)=O

InChI

1S/C21H21N3O2/c22-14-20(25)24-19(12-15-6-2-1-3-7-15)21(26)23-18-11-10-16-8-4-5-9-17(16)13-18/h1-11,13,19H,12,14,22H2,(H,23,26)(H,24,25)

InChI key

YABDXPBHLDPMOA-UHFFFAOYSA-N

General description

Substrate for cathepsin C

Other Notes

Similar to G 4255, but produced by Sigma.

pictograms

Health hazard

signalword

Warning

hcodes

pcodes

Hazard Classifications

Carc. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S Misquith et al.
European journal of biochemistry, 174(4), 691-697 (1988-07-01)
1. Endocytosis of formaldehyde-treated bovine serum albumin by rat liver sinusoidal cells has been followed by injecting rats with the protein labelled with 125I-tyramine cellobiose (125I-TCfBSA). 125I-TCfBSA is quickly taken up by the liver; the radioactivity present in the organ
M Jadot et al.
European journal of biochemistry, 161(3), 695-700 (1986-12-15)
Yeast invertase, when injected into rats, is endocytosed by the liver, mainly by sinusoidal cells. The work reported here aims at investigating the organelles involved in the intracellular journey of this protein. Experiments were performed on rats injected with 125I-invertase
J Hildreth et al.
Biochemical and biophysical research communications, 139(2), 838-844 (1986-09-14)
Cultured fibroblasts from control individuals and two patients affected with the infantile variant of generalized N-acetylneuraminic acid (NeuAc) storage disease were disrupted by nitrogen cavitation, and the post-nuclear supernatant fractions were subjected to subcellular fractionation on Percoll gradients. Accumulating NeuAc
M Jadot et al.
The Biochemical journal, 225(3), 645-648 (1985-02-01)
The release by glycyl-L-phenylalanine 2-naphthylamide (Gly-L-Phe-2-NNap) of endocytosed invertase associated with the MLP fraction (sum of the M, L and P fractions [de Duve, Pressman, Gianetto, Wattiaux & Appelmans (1955) Biochem. J. 63, 604-617]) of rat liver was investigated and
S Akiyama et al.
Cancer research, 45(3), 1005-1007 (1985-03-01)
The cytotoxic activity against human tumor cells of toxic conjugates of Pseudomonas exotoxin with anti-transferrin receptor antibody or epidermal growth factor was potentiated up to 10 to 20-fold by the calcium antagonists verapamil, D-600, and diltiazem and by the lysosomotropic

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