GW10842F
Anti-Rev antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
别名:
Anti-ART/TRS, Anti-Anti-Repression transactivator protein, Anti-Protein Rev
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
viral
manufacturer/tradename
Genway 15-288-10842F
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human immunodeficiency virus 1 ... Rev(155908)
General description
Rev is a regulatory protein of human immunodeficiency virus type 1. It consists of a hydrophobic core, which is formed by binding to another REV molecule and arginine-rich motifs (ARMs).
Immunogen
Immunogen Sequence: GI # 12831140, sequence 1-116
Recombinant Rev protein (HIV-1 vector pNL4-3)
Application
Anti-Rev antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.
Biochem/physiol Actions
Rev is involved in the stabilization and transport of the viral mRNA. It is involved in the up-regulation of the gag- and env-producing mRNAs via cis-acting element in the env region of HIV-1, named rev responsive element. It increases the stability of the unspliced viral mRNA and promotes the transport of the viral mRNA having the rev-responsive element from the nucleus to the cytoplasm.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Xianyang Fang et al.
Cell, 155(3), 594-605 (2013-11-19)
Nuclear export of unspliced and singly spliced viral mRNA is a critical step in the HIV life cycle. The structural basis by which the virus selects its own mRNA among more abundant host cellular RNAs for export has been a
B K Felber et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(5), 1495-1499 (1989-03-01)
rev (trs/art) is an essential human immunodeficiency virus type 1 (HIV-1) regulatory protein. rev increases the levels of the gag- and env-producing mRNAs via a cis-acting element in the env region of HIV-1, named rev-responsive element. Our results show that
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